Publications

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274. Dementia, dementia's risk factors and premorbid brain structure are concentrated in disadvantaged areas: National register and birth-cohort geographic analyses.
Reuben A, Richmond-Rakerd LS, Milne B, Shah D, Pearson A, Hogan S, Ireland D, Keenan R, Knodt AR, Melzer T, Poulton R, Ramrakha S, Whitman ET, Hariri AR, Moffitt TE, Caspi A.
Alzheimers Dement. 2024 Mar 14.

273. A blood biomarker of the pace of aging is associated with brain structure: replication across three cohorts.
Whitman ET, Ryan CP, Abraham WC, Addae A, Corcoran DL, Elliott ML, Hogan S, Ireland D, Keenan R, Knodt AR, Melzer TR, Poulton R, Ramrakha S, Sugden K, Williams BS, Zhou J, Hariri AR, Belsky DW, Moffitt TE, Caspi A; Alzheimer's Disease Neuroimaging Initiative.
Neurobiol Aging. 2024 Jan 24;136:23-33.

272. Test-retest reliability and predictive utility of a macroscale principal functional connectivity gradient.
Knodt AR, Elliott ML, Whitman ET, Winn A, Addae A, Ireland D, Poulton R, Ramrakha S, Caspi A, Moffitt TE, Hariri AR.
Hum Brain Mapp. 2023 Oct 18.

270. Social isolation from childhood to mid-adulthood: is there an association with older brain age?
Lay-Yee R, Hariri AR, Knodt AR, Barrett-Young A, Matthews T, Milne BJ.
Psychol Med. 2023 Jul 24:1-9.

269. Functional topography of the neocortex predicts covariation in complex cognitive and basic motor abilities.
Whitman ET, Knodt AR, Elliott ML, Abraham WC, Cheyne K, Hogan S, Ireland D, Keenan R, Leung JH, Melzer TR, Poulton R, Purdy SC, Ramrakha S, Thorne PR, Caspi A, Moffitt TE, Hariri AR.
Cereb Cortex. 2023 Apr 4:bhad109.

268. Associations Between Thinner Retinal Neuronal Layers and Suboptimal Brain Structural Integrity in a Middle-Aged Cohort.
Barrett-Young A, Abraham WC, Cheung CY, Gale J, Hogan S, Ireland D, Keenan R, Knodt AR, Melzer TR, Moffitt TE, Ramrakha S, Tham YC, Wilson GA, Wong TY, Hariri AR, Poulton R.
Eye Brain. 2023 Mar 11;15:25-35.

267. Improving risk indexes for Alzheimer's disease and related dementias for use in midlife.
Reuben A, Moffitt TE, Abraham WC, Ambler A, Elliott ML, Hariri AR, Harrington H, Hogan S, Houts RM, Ireland D, Knodt AR, Leung J, Pearson A, Poulton R, Purdy SC, Ramrakha S, Rasmussen LJH, Sugden K, Thorne PR, Williams B, Wilson G, Caspi A.
Brain Commun. 2022 Oct 6;4(5):fcac223.

266. Preparedness for healthy ageing and polysubstance use in long-term cannabis users: a population-representative longitudinal study.
Meier MH, Caspi A, Ambler A, Hariri AR, Harrington H, Hogan S, Houts R, Knodt AR, Ramrakha S, Richmond-Rakerd LS, Poulton R, Moffitt TE.
Lancet Healthy Longev. 2022 Oct;3(10):e703-e714.

265. Diminished Structural Brain Integrity in Long-term Cannabis Users Reflects a History of Polysubstance Use.
Knodt AR, Meier MH, Ambler A, Gehred MZ, Harrington H, Ireland D, Poulton R, Ramrakha S, Caspi A, Moffitt TE, Hariri AR.
Biol Psychiatry. 2022 Jun 22:S0006-3223(22)01367-1.

264. Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia.
Sugden K, Caspi A, Elliott ML, Bourassa KJ, Chamarti K, Corcoran DL, Hariri AR, Houts RM, Kothari M, Kritchevsky S, Kuchel GA, Mill JS, Williams BS, Belsky DW, Moffitt TE, Alzheimers Disease Neuroimaging Initiative.
Neurology. 2022 Jul 6:10.1212/WNL.0000000000200898.

262. Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife.
Meier MH, Caspi A, R Knodt A, Hall W, Ambler A, Harrington H, Hogan S, M Houts R, Poulton R, Ramrakha S, Hariri AR, Moffitt TE.
Am J Psychiatry. 2022 Mar 8:appiajp202121060664.

261. Association of Treatable Health Conditions During Adolescence With Accelerated Aging at Midlife.
Bourassa KJ, Moffitt TE, Ambler A, Hariri AR, Harrington H, Houts RM, Ireland D, Knodt A, Poulton R, Ramrakha S, Caspi A.
JAMA Pediatr. 2022 Feb 21:e216417.

257. Association of subcortical gray-matter volumes with life-course-persistent antisocial behavior in a population-representative longitudinal birth cohort
Carlisi CO, Moffitt TE, Knodt AR, Harrington H, Langevin S, Ireland D, Melzer TR, Poulton R, Ramrakha S, Caspi A, Hariri AR, Viding E
Dev Psychopathol. 2021 Oct 18:1-11

254. Long-term Neural Embedding of Childhood Adversity in a Population-Representative Birth Cohort Followed for 5 Decades.
Gehred MZ, Knodt AR, Ambler A, Bourassa KJ, Danese A, Elliott ML, Hogan S, Ireland D, Poulton R, Ramrakha S, Reuben A, Sison ML, Moffitt TE, Hariri AR, Caspi A.
Biol Psychiatry. 2021 Mar 9:S0006-3223(21)01109-4.

253. Midlife Cardiovascular Fitness Is Reflected in the Brain's White Matter.
d'Arbeloff T, Elliott ML, Knodt AR, Sison M, Melzer TR, Ireland D, Ramrakha S, Poulton R, Caspi A, Moffitt TE, Hariri AR.
Front Aging Neurosci. 2021 Apr 6;13:652575.

252. Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy.
Elliott ML, Caspi A, Houts RM, Ambler A, Broadbent JM, Hancox RJ, Harrington H, Hogan S, Keenan R, Knodt A, Leung JH, Melzer TR, Purdy SC, Ramrakha S, Richmond-Rakerd LS, Righarts A, Sugden K, Thomson WM, Thorne PR, Williams BS, Wilson G, Hariri AR, Poulton R, Moffitt TE.
Nat Aging. 2021 Mar;1(3):295-308.

248. Childhood self-control forecasts the pace of midlife aging and preparedness for old age.
Richmond-Rakerd LS, Caspi A, Ambler A, d'Arbeloff T, de Bruine M, Elliott M, Harrington H, Hogan S, Houts RM, Ireland D, Keenan R, Knodt AR, Melzer TR, Park S, Poulton R, Ramrakha S, Rasmussen LJH, Sack E, Schmidt AT, Sison ML, Wertz J, Hariri AR, Moffitt TE.
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2010211118.

246. Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife.
Reuben A, Elliott ML, Abraham WC, Broadbent J, Houts RM, Ireland D, Knodt AR, Poulton R, Ramrakha S, Hariri AR, Caspi A, Moffitt TE.
JAMA. 2020 Nov 17;324(19):1970-1979.

245. Is cardiovascular fitness associated with structural brain integrity in midlife? Evidence from a population-representative birth cohort study.
d'Arbeloff T, Cooke M, Knodt AR, Sison M, Melzer TR, Ireland D, Poulton R, Ramrakha S, Moffitt TE, Caspi A, Hariri AR.
Aging (Albany NY). 2020 Oct 21;12.

243. Association Between Elevated suPAR, a New Biomarker of Inflammation, and Accelerated Aging.
Rasmussen LJH, Caspi A, Ambler A, Danese A, Elliott M, Eugen-Olsen J, Hariri AR, Harrington H, Houts R, Poulton R, Ramrakha S, Sugden K, Williams B, Moffitt TE.
J Gerontol A Biol Sci Med Sci. 2020 Jul 16:glaa178.

242. Pervasively Thinner Neocortex as a Transdiagnostic Feature of General Psychopathology.
Romer AL, Elliott ML, Knodt AR, Sison ML, Ireland D, Houts R, Ramrakha S, Poulton R, Keenan R, Melzer TR, Moffitt TE, Caspi A, Hariri AR.
Am J Psychiatry. 2020 Jun 30:appiajp202019090934

240. What is the Test-Retest Reliability of Common Task-fMRI Measure? New Empirical Evidence and a Meta-Analysis
Elliott ML, Knodt AR, Ireland D, Morris ML, Poulton R, Ramrakha S, Sison ML, Moffitt TE, Caspi A, Hariri AR.
Psychol Sci. 2020 Jun 3:956797620916786

237. Longitudinal Assessment of Mental Health Disorders and Comorbidities Across 4 Decades Among Participants in the Dunedin Birth Cohort Study.
Caspi A, Houts RM, Ambler A, Danese A, Elliott ML, Hariri A, Harrington H, Hogan S, Poulton R, Ramrakha S, Rasmussen LJH, Reuben A, Richmond-Rakerd L, Sugden K, Wertz J, Williams BS, Moffitt TE.
JAMA Netw Open. 2020 Apr 1;3(4):e203221

234. Associations between life-course-persistent antisocial behaviour and brain structure in a population-representative longitudinal birth cohort.
Carlisi CO, Moffitt TE, Knodt AR, Harrington H, Ireland D, Melzer TR, Poulton R, Ramrakha S, Caspi A, Hariri AR, Viding E.
Lancet Psychiatry. 2020 Mar;7(3):245-253.

232. White matter hyperintensities are common in midlife and already associated with cognitive decline.
d'Arbeloff T, Elliott ML, Knodt AR, Melzer TR, Keenan R, Ireland D, Ramrakha S, Poulton R, Anderson T, Caspi A, Moffitt TE, Hariri AR.
Brain Commun. 2019;1(1):fcz041.

231. Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort.
Elliott ML, Belsky DW, Knodt AR, Ireland D, Melzer TR, Poulton R, Ramrakha S, Caspi A, Moffitt TE, Hariri AR.
Mol Psychiatry. 2019 Dec 10.

230. Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort.
Romer AL, Knodt AR, Sison ML, Ireland D, Houts R, Ramrakha S, Poulton R, Keenan R, Melzer TR, Moffitt TE, Caspi A, Hariri AR.
Mol Psychiatry. 2019 Dec 3.

226. Association of Neurocognitive and Physical Function With Gait Speed in Midlife.
Rasmussen LJH, Caspi A, Ambler A, Broadbent JM, Cohen HJ, d'Arbeloff T, Elliott M, Hancox RJ, Harrington H, Hogan S, Houts R, Ireland D, Knodt AR, Meredith-Jones K, Morey MC, Morrison L, Poulton R, Ramrakha S, Richmond-Rakerd L, Sison ML, Sneddon K, Thomson WM, Hariri AR, Moffitt TE.
JAMA Netw Open. 2019 Oct 2;2(10):e1913123.

213. General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks.
Elliott ML, Knodt AR, Cooke M, Kim MJ, Melzer TR, Keenan R, Ireland D, Ramrakha S, Poulton R, Caspi A, Moffitt TE, Hariri AR.
Neuroimage. 2019 Jan 29. pii: S1053-8119(19)30074-6.

208. A Polygenic Score for Higher Educational Attainment is Associated with Larger Brains.
Elliott ML, Belsky DW, Anderson K, Corcoran DL, Ge T, Knodt A, Prinz JA, Sugden K, Williams B, Ireland D, Poulton R, Caspi A, Holmes A, Moffitt T, Hariri AR.
Cereb Cortex. 2018 Sep 12.